BDBM50304196 CHEMBL593860::N-[4-(Benzo[d]thiazol-2''-yl)-3-hydroxyphenyl]-6'-methoxy-7'-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4'-amine

SMILES COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(OC)c3)ncnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=UJBJAMOSBBJZBK-UHFFFAOYSA-N

Data  8 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304196   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304196(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Affinity DataIC50:  2nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM50304196(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Affinity DataEC50:  9.40E+3nMAssay Description:Inhibition of EGFR in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed